RAF Typhoon jets have operated alongside France's air force in a joint strike against an hidden munitions depot in Syrian territory operated by the IS group, according to the British defence ministry.
The location, identified by surveillance, was believed to be storing arms and explosives, the announcement noted, and was positioned in mountains just above the historic site of Palmyra in Syria's central region.
"The RAF jets utilized precision-guided Paveway IV munitions to target a series of entry passages providing entry to the depot... preliminary assessments indicate the target was engaged successfully," officials stated.
There was no sign of any civilian impact in the operation on Saturday evening and all the aircraft returned safely, the MoD added.
The Typhoon FGR4s were assisted by a Voyager aerial refuelling aircraft.
The Islamic State group - referred to as ISIS - enforced jihadist rule over significant areas in Syria and Iraq until 2019.
"This strike shows our UK leadership, and resolve to operate in unison with our allies, to eliminate any revival of IS and their harmful and extremist ideologies in the region," the British Defence Secretary the Defence Secretary said.
RAF aircraft have performed surveillance missions over Syria to "forestall any attempted resurgence" of IS after its routing at the Baghuz confrontation in 2019, the authorities noted.
"I must thank all the members of our armed forces participating in this strike for their expertise and their bravery," he commented. "They were part of numerous British personnel on duty over Christmas and New Year. This mission, to eliminate terrorist threats who threaten our safety, shows how UK forces are prepared to act, all year round, keeping Britain secure domestically and strong abroad."
Last December, the US military conducted what it called a "major assault" on Daesh sites in the country, following an attack resulted in the deaths of two American soldiers and a local interpreter in Palmyra.
The U.N. says IS still boasts an estimated 5,000 to 7,000 militants in Iraq and Syria.